Debra I. Diz, Ph.D
Professor and Director of Basic Sciences Research, Hypertension & Vascular Research Center; Professor, Surgical Sciences; Professor, Department of Physiology & Pharmacology; Neuroscience Program
Hanes Building – 6th floor
Medical Center Boulevard
Winston-Salem, NC 27157-1032
Tel: 336-716-2150
Fax: 336-716-2456
Email: ddiz@wfubmc.edu
Education:
Randolph-Macon Woman’s College, BA, 1976
University of Tennessee Center for Health Sciences, PhD, 1980
Research Topics:
Neuropharmacology of hypertension
Receptors
Aging and neural control of the circulation
Current Research:
Dr. Diz’s research has identified the neuroanatomical and transmitter pathways subserving angiotensin II actions in brain areas involved in baroreceptor reflex control of the circulation. Long-standing studies investigate neural and hormonal interactions in the kidney and alterations in responsiveness to angiotensin peptides in renal ischemia, hypertension and most recently during aging. Her research has been funded continuously by NIH, NHLBI since 1986. She was an Established Investigator of the AHA from 1989 to 1994. She is currently co-director of the Program Project Grant HL-51952. She has participated in NIH and AHA peer review systems since 1988 including the NHLBI Program Project Review Committee and the NIGMS Minority Access to Research Careers Review Committee. She has collaborations with many outside investigators including those at WSSU & NCCU to foster development of minority faculty and students in the biomedical sciences.
Selected Recent Publications:
For a listing of additional publications, refer to PubMed, a service provided by the National Library of Medicine.
Shaltout HA, Figueroa JP, Rose JC, Diz DI, Chappell MC. Alterations in Circulatory and Renal Angiotensin-Converting Enzyme and Angiotensin-Converting Enzyme 2 in Fetal Programmed Hypertension. Hypertension. 2008 Dec 1. [Epub ahead of print]
Diz DI. Future directions in cardiovascular pharmacology: examples from the Renin-Angiotensin system. Mol Interv. 2008 Oct;8(5):222-5.
Diz DI, Garcia-Espinosa MA, Gallagher PE, Ganten D, Ferrario CM, Averill DB. Angiotensin-(1-7) and baroreflex function in nucleus tractus solitarii of (mRen2)27 transgenic rats. J Cardiovasc Pharmacol. 2008 Jun;51(6):542-8.
Diz DI. Lewis K. Dahl memorial lecture: the renin-angiotensin system and aging. Hypertension. 2008 Jul;52(1):37-43.
Awumey EM, Hill SK, Diz DI, Bukoski RD. Cytochrome P-450 metabolites of 2-arachidonoylglycerol play a role in Ca2+-induced relaxation of rat mesenteric arteries. Am J Physiol Heart Circ Physiol. 2008 May;294(5):H2363-70.