Anna Misior, Ph.D.

Postdoctoral Fellow

Lineberger Comprehensive Cancer Center
UNC-Chapel Hill

Education:

Ph.D., Molecular Medicine, 2008
Wake Forest University Graduate School of the Arts & Sciences
Winston-Salem, NC

BS, Biology/Chemistry, 2001
Mars Hill College, Mars Hill, NC

Certified Clinical Research Coordinator, 2002-2006; ACRP

 

Research Interest:

Intracellular signaling events which regulate growth of human airway smooth muscle cells in response to inflammation and relevant pharmacological agents (primarily corticosteroids and COX-2 inhibitors). 

Publications:

Misior AM, Deshpande DA, Loza MJ, Pascual RM, Hipp JD, Penn RB. Glucocorticoid- and Protein Kinase A- dependent Transcriptome Regulation in Airway Smooth Muscle. Am J Respir Cell Mol Biol. 2008 Dec 4. [Epub ahead of print]

Kong KC, Gandhi U, Martin TJ, Anz CB, Yan H, Misior AM, Pascual RM, Deshpande DA, Penn RB. Endogenous Gs-coupled receptors in smooth muscle exhibit differential susceptibility to GRK2/3-mediated desensitization. Biochemistry. 2008 Sep 2;47(35):9279-88. Epub 2008 Aug 9.

Misior AM, Yan H, Pascual RM, Deshpande DA, Panettieri RA, Penn RB. Mitogenic effects of cytokines on smooth muscle are critically dependent on protein kinase A and are unmasked by steroids and cyclooxygenase inhibitors. Mol Pharmacol. 2008 Feb;73(2):566-74. Epub 2007 Nov 9.

Huang YS, Misior A, Li LW. Novel role and regulation of the interleukin-1 receptor associated kinase (IRAK) family proteins. Cell Mol Immunol. 2005 Feb;2(1):36-9. Review.