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Office of Technology Asset Management at Wake Forest University School of Medicine


 

Novel Silicon Substituted Dienes and their Cycloadducts

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Inventors: Welker, Pidaparthi

 

TECHNOLOGY DESCRIPTION:

Researchers in the Department of Chemistry at Wake Forest University have developed novel silicon substituted dienes. These dienes and their cycloadducts are useful components for a number of commercial products, including:

 

silicone-containing polyester resins

polyamide resins

silane coupling agents

plasticizers for vinyl chloride

curing agents for epoxy resins

pharmaceuticals & agricultural products

Unlike existing silicon substituted dienes, these novel compounds are produced in high yield, enhance exo-selectivity in Diels-Alder cycloaddition reactions, and are significantly more stable than other highly reactive silicon dienes such as “Danishefsky’s diene”. Furthermore, these new reagents exist as solids at room temperature, which confers additional advantages in terms of purification and ease of use.

 

MATERIALS:

Samples of the silicon substituted dienes are available for research purposes from Strem Chemicals.

 

ADDITIONAL INFORMATION:

Organic Letters, 2007, 9(9), 1623-1626

2,2',2"-Nitrilotris(ethanolato)(buta-1,3-dien-2-yl)silane

Bis(1,2-benzenediolato)(1,3-butadien-2-yl)silicate

 

 

Licensing Contact:

Stephen J. Susalka, Ph.D.

Assistant Director

Email: ssusalka@wfubmc.edu

Phone: (336) 716-3729