Wireless Systems for Detection, Processing, and Activation of Neural Events Using Onboard Computer Control

Inventors: Drs. Sam A.  Deadwyler and Robert E. Hampson

PDF of Executive Summary

OVERVIEW

Knowledge of brain function and the neurodevice market ($5.5 billion) are both growing rapidly, as is the need for better and more convenient methods of observing and interacting with the brain.  Unfortunately, the systems currently employed to record and stimulate neural activity directly  via  implanted electrodes remain inconvenient and impede collection of meaningful biological data.  

INVENTION

Researchers at the Wake Forest University School of Medicine have developed a compact system that analyzes, compresses, and then transmits cognitively relevant neural action potential data wirelessly from subject to computer via the most current Bluetooth technology.  The system can transmit action potential waveform  and time-stamp data from identified neurons in awake, behaving subjects while engaged in cognitive tasks.  In addition, it can be employed to wirelessly program stimulation of the same neural tissue via the electrodes that record signals.  The system can be used for basic research, for small mammals such as mice, or as part of a system to monitor, diagnose and even  treat brain disorders in humans. 

UNIQUE PROPERTIES

· Scientifically validated prototype:  Tested in laboratory settings (J. Neurosci. Methods)

· Record individual neuron firing data, for longer times and distances (30 meters).

· Configurable self-contained stimulation and recording methodology

· Study the neural basis of natural behaviors not possible via other wireless systems.

· Develop better, more convenient brain-machine interfaces for neuromodulation (a $1.38 billion market) and neuroprosthetics (a $540 million market).

· Simplify surgical procedures for  neural recordings                           (Neurosurgical Market: $2.5 Billion)

   STATUS