Publications from 2004 to the Present
David W. Busija, Ph.D., Professor
1. Erdős B, Snipes JA, Miller AW, Busija DW. Cerebrovascular dysfunction in Zucker obese rats is mediated by oxidative stress and protein kinase C. Diabetes 53: 1352-1359, 2004. 2. Erdős B, Snipes JA, Miller AW, Busija DW. Subtype specific potassium channel dysfunction in cerebral arteries of insulin-resistant rats is mediated by reactive oxygen species. Stroke 35: 964-969, 2004. 3. Kis B, Nagy K, Snipes JA, Rajapakse N, Horiguchi T, Grover GJ, Busija DW. The mitochondrial KATP channel opener BMS191095 induces neuronal preconditioning. Neuroreport 15:345-349, 2004. 4. Miller AW, Tulbert C, Busija DW. Rosuvastatin treatment reverses impaired coronary artery vasodilation in fructose-fed insulin resistant rats. Am J Physiol 287: R157-R160, 2004. 5. Kis B, Snipes JA, Bari F, Busija DW. Regional distribution of cyclooxygenase-3 mRNA in the rat central nervous system. Mol Brain Res 126: 78-80, 2004. 6. Busija DW, Lacza Z, Rajapakse N, Shimizu K, Kis B, Bari F, Domoki F, Horiguchi T. Targeting mitochondrial ATP-sensitive potassium channels—A novel approach to neuroprotection. Brain Res Rev 46: 282-294, 2004. 7. Nagy K, Kis B, Rajapakse NC, Bari F, Busija DW. Diazoxide preconditioning protects against neuronal cell death by attenuation of oxidative stress upon glutamate stimulation. J Neurosci Res 76:697-704, 2004. 8. Lacza Z, Snipes JA, Zhang J, Horvath EM, Figureroa JP, Szabo C, Busija DW. Lack of mitochondrial nitric oxide production in the brain. J Neurochem 90: 942-951, 2004. 9. Domoki F, Bari F, Nagy K, Busija DW, Siklos L. Diazoxide prevents mitochondrial swelling and Ca (2+) accumulation in CAI pyramidal cells after cerebral ischemia in newborn pigs. Brain Research 1019: 97-104, 2004. 10. Busija DW, Miller AW, Katakam P, Simanle S, Erdős B. Mechanisms of vascular dysfunction in insulin resistance. Cur Opin Invest Drugs 5:929-935, 2004. 11. Erdős B, Snipes JA, Kis B, Miller AW, Busija DW. Vasoconstrictor mechanisms in the cerebral circulation are unaffected by insulin resistance. Am J Physiol 287:R1456-61, 2004. 12. Kis B, Snipes JA, Simandle SA, Busija DW. Acetaminophen-sensitive prostaglandin production in rat cerebral endothelial cells. Am J Physiol 288:R897-902, 2005. 13. Katakam P, Tulbert CD, Snipes JA, Erdos B, Miller AW, Busija DW. Impaired insulin-induced vasodilation in small coronary arteries of Zucker Obese rats is mediated by reactive oxygen species. Am J Physiol 288:H854-860, 2005. 14. Horiguchi T, Snipes JA, Kis B, Shimizu S, Busija DW. The role of nitric oxide in the development of cortical spreading depression-induced tolerance to transient focal cerebral ischemia in rats. Brain Res 1039:84-89, 2005. 15. Snipes JA, Kis B, Shelness GS, Hewett JA, Busija DW. Cloning and Characterization of Cyclooxygenase-1b (putative COX-3) in Rat. J Pharmacol Exp Ther 313:668-676, 2005. 16. Kis B, Ueta Y, Busija DW. Peptide mediators of the brain endothelium. In: Handbook of Neurochemistry. In press, 2006. 17. Chen L, Kis B, Busija DW, Yamashita H, Ueta Y. Adenomedullin protects rat cerebral endothelial cells from oxidant damage in vitro. Regul Pept 130:27-34, 2005. 18. Domoki F, Kis B, Nagy K, Farkas E, Busija DW, Bari F. Diazoxide preserves hypercapnia-induced arteriolar vasodilation after global cerebral ischemia in piglets. Am J Physiol 289:H368-373, 2005. 19. Busija DW, Katakam P, Rajapakse NC, Kis B, Grover G, Domoki F, Bari F. Effects of ATP-sensitive potassium channel activators diazoxide and BMS-191095 on membrane potential and reactive oxygen species production in isolated piglet mitochondria. Brain Res Bull 66:85-90, 2005. 20. Simandle S, Kerr BA, Lacza Z, Eckman D, Busija DW, Bari F. Piglet pial arteries respond to NMDA in vivo but not in vitro. Microvas Res 70:76-83, 2005. 21. Simandle S, Erdos B, Snipes JA, Miller AW, Busija DW. Insulin resistance does not impair contractile responses of cerebral arteries. Life Sci 16:2262-2272, 2005. 22. Kis B, Snipes JA, Busija DW. Acetaminophen and the COX-3 puzzle: Sorting out Facts, Fictions, and Uncertainties. J Pharmacol Exp Ther 315:1-7, 2005. 23. Lenzser G, Kis B, Bari F, Busija DW. Diazoxide preconditioning attenuates global cerebral ischemia-induced blood-brain barrier permeability. Brain Res 105:72-80, 2005. 24. Lacza Z, Horvath EM, Pankotai E, Csordas, Kollai M, Szabo C, Busija DW. The novel red-fluorescent probe DAR-4M measures reactive nitrogen species rather than NO. J Pharmacol Toxicol Meth 52:335-340, 2005. 25. Lacza Z, Pankotai E, Csordas A, Gero D, Kiss L, Horvath EM, Kollai M, Busija DW, Szabo C. Mitochondrial NO and reactive nitrogen species production: Does mtNOS exist? Nitric Oxide 14:162-168, 2006. 26. Busija DW, Miller AW, Katakam P, Erdos B. Insulin resistance and associated dysfunction of resistance vessels and arterial hypertension. Minerva Medica 96:223-232, 2005. 27. Horiguchi T, Kis B, Rajapakse N, Shimizu K, Busija DW. Cortical spreading depression-induced tolerance to transient focal cerebral ischemia in halothane anesthetized rats is affected by anesthetic level but not ATP-sensitive potassium channels. Brain Res 1062(1-2):127-33, 2005. 28. Erdős B, Tulbert C, Snipes JA, Busija DW. Rosuvastatin reduces NAD(P)H-oxidase-dependent superoxide anion production and improves vascular function in cerebral arteries of Zucker obese rats. Am J Physiol 290:H1264-1270, 2006. 29. Katakam PVG, Tulbert C D, Busija DW. Impaired Endothelin-Induced Vasoconstriction in Coronary Arteries of Zucker Obese Rats is Associated with Uncoupling of Ca2+ Signaling. Am J Physiol Regul Integr Comp Physiol, special issue on Metabolic Syndrome, 290:R145-153, 2006. 30. Busija DW, Miller AW, Katakam P, Erdos B. Adverse effects of reactive oxygen species on vascular reactivity in insulin resistance. Antioxidants and Redox Signaling, in press, 2005.
31. Kis B, Isse T, Snipes JA, Chen L, Yamashita H, Ueta Y, Busija DW. Effects of LPS stimulation on the expression of prostaglandin carriers in the cells of the blood-brain and blood-cerebrospinal fluid barriers. J Appl Physiol, special issue on Fever, 100:1392-1399, 2005. 32. Kis B, Chen L, Ueta Y, Busija DW. Autocrine peptide mediators of cerebral endothelial cells and their role in the regulation of blood-brain barrier. Peptides 27:211-222, 2006. 33. Bari F, Nagy K, Guidett P, Schwarcz R, Busija DW, Domoki F. Kynurenic acid attenuates NMDA-induced pial arteriolar dilation in newborn pigs. Brain Res 1069:39-46, 2006. 34. Lacza Z, Busija DW. Urotensin-II is a nitric oxide-dependent vasodilator in the pial arteries of the newborn pig. Life Sciences, in press, 2006. 35. Horvath EM, Lacza Z, Csordas A, Szabo C, Kollai M, Busija DW. Graft derived cells with double nuclei in the penumbral region of experimental brain trauma. Neurosci Lett 396:182-186, 2005. 36. Lacza Z, Kozlov AV, Pankotai E, Csordas A, Wolf G, Redl H, Kollai M, Szbo C, Busija DW, Horn TFW. Mitochondria produce reactive nitrogen species via an arginine-independent pathway. Free Rad Res 40:369-378, 2006. 37. Gaspar T, Kis B, Snipes J, Lenzser G, Mayanagi K, Bari F, Busija D. Transient glucose and amino acid deprivation induces delayed preconditioning in cultured rat cortical neurons. J Neurochem, in press, 2006. 38. Horiguchi T, Snipes JA, Kis B, Shimizu K, Busija DW. Cyclooxygenase-2 mediates the development of cortical spreading depression (CSD) – induced tolerance to transient focal cerebral ischemia in rats. Neuroscience, in press, 2006. 39. Kis B, Snipes JA, Gaspar T, Lenszer G, Tulbert CD, Busija DW. Cloning of cyclooxygenase-1b (putative COX-3) in mouse. J Inflam Res, in press, 2006. 40. Mayanagi K, Kis B, Gaspar T, Busija DW. Protective role of BMS-191095 via activation of mitochondrial KATP channels against neuronal damage following experimental strokes in rats. J Cereb Blood Flow Metabol, in press, 2006. |