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Department of Physiology and Pharmacology

N. Tannu, D.C. Mash, and S.E. Hemby (Accepted for publication: Molecular Psychiatry). Cytosolic proteomic alterations in the nucleus accumbens of cocaine overdose victims.

 

S.E. Hemby, Joann O’Connor, G. Acosta, D. Floyd, N. Anderson, B.A. McCool, D. Friedman, K.A. Grant. (Accepted for publication: Alcoholism: Clinical and Experimental Research). Ethanol-induced regulation of GABAA subunit mRNAs in prefrontal fields of cynomolgus monkeys.

 

J.A. O’Connor, E.C. Muly, S.E. Arnold and S.E. Hemby (Accepted for publication: Schizophrenia Research). AMPA receptor subunit and splice variant expression in the DLPFC of schizophrenic subjects and rhesus monkeys chronically administered antipsychotic drugs.

 

N. Tannu and S.E. Hemby (Accepted for publication: Nature Protocols). Two dimensional fluorescence difference gel electrophoresis (2D-DIGE) for comparative proteomics profiling.

 

S.E. Hemby and J.A. O’Connor. Transcriptional regulation in schizophrenia. In: E.F. Walker and D. Romer, (eds.), Adolescent Psychopathology and the Developing Brain:  Integrating Brain and Prevention Science, Oxford University Press: New York (in press).

 

S.E. Hemby. Assessment of genome and proteome profiles in cocaine abuse. In: S.E. Hemby and S. Bahn (eds.), Functional Genomics and Proteomics in the Clinical Neurosciences. Elsevier: New York (in press)

 

N. Tannu and S.E. Hemby. Methods for proteomics in neuroscience. In: S.E. Hemby and S. Bahn (eds.), Functional Genomics and Proteomics in the Clinical Neurosciences. Elsevier: New York (in press).

 

J. O’Connor, W. Hasenkamp, B. Horman, E.C. Muly and S.E. Hemby (2006). Region specific regulation of NR1 subunit in rhesus monkeys following chronic antipsychotic drug administration. Biological Psychiatry, 60:659-662.

 

N. Tannu and S.E. Hemby (2006). Quantitation in two dimensional fluorescence difference gel electrophoresis (2DIGE): effect of protein fixation. Electrophoresis, 27:2011-1015.

 

J. O’Connor, E.C. Muly, S.E. Hemby. (2006). Molecular mapping of striatal subregions in Macaca Mulata. Experimental Neurology, 198:326-337.

 

S.D. Ginsberg, S.E. Hemby, E.J. Mufson and L.J. Martin (2005). Cell and tissue microdissection in combination with genomic and proteomic applications, In: L. Zaborszky, F.G. Wouterlood, J.L. Lanciego (eds.), Neuroanatomical Tract-Tracing 3: Molecules - Neurons & Systems. Springer/Kluwer/Plenum Publishers, Amsterdam, pp. 109-141.

 

J.E. Smith, C. Co, M. Coller, S.E. Hemby and T.J. Martin (2006). Heroin potentates the reinforcing effects of cocaine and enhances the effects of cocaine on the extracellular fluid levels of nucleus accumbens dopamine. Neuropsychopharmacology, 31:139-150.

 

S. E. Hemby, W. Tang, E.C. Muly, M.J. Kuhar, L. Howell, D.C. Mash (2005). Cocaine-induced alterations in nucleus accumbens ionotropic glutamate receptor subunits in human and non-human primates. Journal of Neurochemistry, 95:1785-1793.

 

S.E. Hemby, W.Tang, and B. Horman (2005). Regulation of glutamate receptor subunits following cocaine self-administration. Brain Research, 1064:75-82.

 

J. M. Verkuyl, S.E. Hemby and M. Joëls. (2004). Chronic stress attenuates GABAergic inhibition and alters gene expression of parvocellular neurons in the hypothalamus. European Journal of Neuroscience 6:665-1673.

 

Hemby, S.E. (2004). Morphine-induced alterations in gene expression of calbindinimmunopositive neurons in nucleus accumbens shell and core. Neuroscience 126: 689-703.

Tang, W., M. Wesley, W.M. Freeman, B. Liang, and S.E. Hemby (2004). Alterations in ionotropic glutamate receptor subunits during cocaine self-administration and withdrawal in rats. Journal of Neurochemistry 89:1021-1033.

Freeman, W.M. and S.E. Hemby (2004). Proteomics for protein expression profiling in neuroscience. Journal of Neurochemical Research 29: 1065-1083.

S.D. Ginsberg, I. Elarova, M. Ruben, F. Tan, S.E. Counts, J.H. Eberwine, J.Q. Trojanowski, S.E. Hemby, E.J. Mufson, and S. Che (2004). Single cell gene expression analysis: implications for neurodegenerative and neuropsychiatric disorders. Journal of Neurochemical Research, 29:1053-64.

 

W.H. Fasulo and S.E. Hemby (2004). Signal transduction abnormalities in schizophrenia: new treatment options, In: J.A. den Boer, G.J. ter Horst, and M. George (eds.), Current and Future Developments in Psychopharmacology. Benecke N.I., Amsterdam, pp. 231-256.

 

Backes, E. and S. E. Hemby (2003). Discrete cell gene profiling of ventral tegmental dopamine neurons following acute and chronic cocaine celf-administration. J Pharmacol Exp Ther 307: 450-459.

Fasulo, W. H. and S. E. Hemby (2003). Time-dependent changes in gene expression profiles of midbrain dopamine neurons following haloperidol administration. Journal of Neurochemistry 87: 205-219.

Tang, W. X., W. H. Fasulo, D. C. Mash and S. E. Hemby (2003). Molecular profiling of midbrain dopamine regions in cocaine overdose victims. Journal of Neurochemistry 85: 911-24.

Hemby, S. E., J. Q. Trojanowski and S. D. Ginsberg (2003). Neuron-specific age-related decreases in dopamine receptor subtype mRNAs. J Comp Neurol 456: 176-83.

S.E. Hemby (2003). The neurobiology of alcohol addiction. In: B.A. Johnson, P. Ruiz, and M. Glanter (eds.) Alcoholism: A Practical Handbook. Lippincott Williams & Wilkins, Baltimore pp. 10-18.

 

 Hasenkamp, W. and S. E. Hemby (2002). Functional genomics and psychiatric illness. Progress in Brain Research 138: 375-93.

 Hemby, S. E., S. D. Ginsberg, B. Brunk, S. E. Arnold, J. Q. Trojanowski and J. H. Eberwine (2002). Gene expression profile for schizophrenia: discrete neuron transcription patterns in the entorhinal cortex. Arch Gen Psychiatry 59: 631-40.

 Kaech, S. M., S. Hemby, E. Kersh and R. Ahmed (2002). Molecular and functional profiling of memory CD8 T cell differentiation. Cell 111: 837-51.

  Hemby, S. E., M. M. Sanchez and J. T. Winslow (2001). Functional genomics approaches to a primate model of autistic symptomology. Journal of Autism and Developmental Disorders 31: 551-5.

 

 Ginsberg, S. D., S. E. Hemby, V. M. Lee, J. H. Eberwine and J. Q. Trojanowski (2000). Expression profile of transcripts in Alzheimer's disease tangle-bearing CA1 neurons. Annals of Neurology 48: 77-87.

 Ginsberg, S. D., P. B. Crino, S. E. Hemby, J. A. Weingarten, V. M. Lee, J. H. Eberwine and J. Q. Trojanowski (1999). Predominance of neuronal mRNAs in individual Alzheimer's disease senile plaques. Annals of  Neurology 45: 174-81.

 

 Hemby, S. E., C. Co, S. I. Dworkin and J. E. Smith (1999). Synergistic elevations in nucleus accumbens extracellular dopamine concentrations during self-administration of cocaine/heroin combinations (Speedball) in rats. Journal of Pharmacology and Experimental Therapeutics 288: 274-80.

 

 Hemby, S. E. (1999). Recent advances in the biology of addiction. Current Psychiatry Reports 1: 159-65.

 

 Crino, P., K. Khodakhah, K. Becker, S. Ginsberg, S. Hemby and J. Eberwine (1998). Presence and phosphorylation of transcription factors in developing dendrites. Proceedings of the National Academy of Sciences U S A 95: 2313-8.