Pulmonary & Critical Care

Diseases and Conditions

Procedures and Treatments

Clinics/Patient Information

Locate A Physician

Referrals

Research

Education

Faculty

Norman Adair, MD

Eugene R. Bleecker, MD

Arjun Bijoy (Raja) Chatterjee, M

Robert Chin, MD

John Conforti, DO

Annette Hastie, PhD

Gregory Hawkins, PhD

Duncan Hite, MD

Wendy Moore, MD

Peter Morris, MD

Josyf Mychaleckyj, MA, DPhil

Jill Ohar, MD

Rodolfo Pascual, MD

Mary Fontana-Penn, MD

Raymond Penn, PhD

Stephen P. Peters, MD, PhD

Michael Seeds, PhD

Siqun (Lilly) Zheng, MD

index

Staff

WFUBMC Home

>

PCC

>

Faculty

>

Josyf Mychaleckyj, MA, DPhil

Josyf Mychaleckyj, MA, DPhil                                    In a former academic life I was a theoretical chemist, obtaining my doctorate from the University of Oxford in 1989, where I specialized in the application of quantum and classical mechanics to model chemical reaction dynamics under the influence of lasers. I left academia to experience the business world and commercial computing first hand, and spent 6 years at Oracle Corporation in Redwood Shores, California where I led product development teams, and very large projects to architect and design complex database systems, consulting for some of the world's largest high-tech companies. Always desirous of returning to academia, in 1997 I joined the Whitehead Institute/ MIT Center for Genome Research as a senior member of the informatics group, at a very dynamic moment, when the Human Genome Project was beginning to ramp up to full production sequence output. In 1999, a family relocation landed me at Wake Forest where I now focus on genomics applied to complex disease mapping, with diabetes as a disease specialty. My work has included mapping and cloning susceptibility genes for type 1, type 2, and MODY diabetes, diabetic nephropathy, as well as other work in prostate cancer. My lab uses contemporary bioinformatics techniques both in genome mapping, and to characterize the detailed structure and function of individual genes. Recently I have started collaborations utilizing microarray data to understand stem cell transcriptomes, host-pathogen interactions, mouse pheromone memory, and the progression of type 1 diabetic nephropathy. I am a collaborator in the International Type 1 Diabetes Genetics Consortium Coordinating Center, and chair the Consortium Bioinformatics Committee. I serve on NIH and Foundation bioinformatics review panels.