Our Role as Clinical Investigators -- What It Means to You
Our doctors are also clinical investigators who work to identify the new treatments of tomorrow. A sample of their medical publications – more than 100 in 2008 – is below. Also included are their book publications, illustrating their prominence in the field of urology. Because our doctors are at the forefront of discovery and leaders in the field, we can offer you the newest treatments and technology, often before they are widely available.
Dean Assimos, M.D.
● Prevalence of hyperoxaluria after bariatric surgery. Patel BN, Passman CM, Fernandez A, Asplin JR, Coe FL, Kim SC, Lingeman JE, Assimos DG. J Urol. 2009 Jan;181(1):161-6.
● Role of laparoscopic stone surgery. Desai RA, Assimos DG. Urology. 2008 Apr;71(4):578-80.
● Accuracy of urinary dipstick testing for pH manipulation therapy. Desai RA, Assimos DG.
J Endourol. 2008 Jun;22(6):1367-70.
For a complete listing of publications, go to the following link on PubMed, a service provided by the National Library of Medicine: <All>
Anthony Atala, M.D.
● Biomaterials and tissue engineering in urology, Edited by J Denstedt, University of
Western Ontario, Canada and A. Atala, Wake Forest Institute for Regenerative Medicine.
● Minimally Invasive Procedures in Urology, by Steven A. Kaplan (Editor) , Alan W. Partin (Editor) , Anthony J. Atala (Editor).
● Regenerative medicine and tissue engineering in urology. Atala A. Urol Clin North Am. 2009 May;36(2):199-209.
● New frontiers in stem cell research and therapy. Atala A. Curr Stem Cell Res Ther. 2009 Jan;4(1):1.
● Stem cells in urology. Aboushwareb T, Atala A. Nat Clin Pract Urol. 2008 Nov;5(11):621-31. Epub 2008 Oct 14. Review.
● Urine derived cells are a potential source for urological tissue reconstruction. Zhang Y, McNeill E, Tian H, Soker S, Andersson KE, Yoo JJ, Atala A. J Urol. 2008 Nov;180(5):2226-33. Epub 2008 Sep 20.
● Bioengineered tissues for urogenital repair in children. Atala A. Pediatr Res. 2008 May;63(5):569-75. Review.
● Bioengineered Tissues For Urogenital Repair In Children. Atala A. Pediatr Res. 2008 Jan 24. [Epub ahead of print]
For a complete listing of publications, go to the following link on PubMed, a service provided by the National Library of Medicine: <All>
Gopal Badlani, M.D.
● Effects of long-term dietary soy treatment on female urethral morphology and function in ovariectomized nonhuman primates. Gratzke C, Jarajapu YP, Christ GJ, Kaplan JR, Williams JK, Andersson KE, Badlani G. J Urol. 2008 Nov;180(5):2247-53. Epub 2008 Sep 20.
● A 20-year experience with percutaneous resection of upper tract transitional carcinoma: is there an oncologic benefit with adjuvant bacillus Calmette Guérin therapy? Rastinehad AR, Ost MC, Vanderbrink BA, Greenberg KL, El-Hakim A, Marcovich R, Badlani GH, Smith AD. Urology. 2009 Jan;73(1):27-31. Epub 2008 Oct 17.
● Continence: Current Concepts and Treatment Strategies. Badlani, G.H.; Davila, G.W.; Michel, M.C.; Rosette, J.J.M.C.H. de la (Eds.) 2009.
● The Science behind Biomaterials in Female Stress Urinary Incontinence Surgery. Amrute KV, Badlani GH.ScientificWorldJournal. 2009 Jan 18;9:23-31.
● High-energy transurethral thermotherapy with CoreTherm approaches transurethral prostate resection in outcome efficacy: a meta-analysis. Kaye JD, Smith AD, Badlani GH, Lee BR, Ost MC. J Endourol. 2008 Apr;22(4):713-8.
For a complete listing of publications, go to the following link on PubMed, a service provided by the National Library of Medicine: <All>
Ashok Hemal, M.D.
● Robotic and laparoscopic radical cystectomy in the management of bladder cancer. Hemal AK. Curr Urol Rep. 2009 Jan;10(1):45-54.
● Robot assisted laparoscopic pyeloplasty in patients of ureteropelvic junction obstruction with previously failed open surgical repair. Hemal AK, Mishra S, Mukharjee S, Suryavanshi M. Int J Urol. 2008 Aug;15(8):744-6.
● A prospective comparison of laparoscopic and robotic radical nephrectomy for T1-2N0M0 renal cell carcinoma. Hemal AK, Kumar A. World J Urol. 2008 Aug 13. [Epub ahead of print]
For a complete listing of publications, go to the following link on PubMed, a service provided by the National Library of Medicine: <All>
Steve Hodges, M.D.
● A randomized placebo-controlled study of the efficacy of antimuscarinics in the treatment of pediatric overactive bladder and incontinence. Hodges SJ, Atala A. Curr Urol Rep. 2009 Jan;10(1):6-7.
● Voiding pattern analysis as a surrogate for cystometric evaluation in uroplakin II knockout mice. Hodges SJ, Zhou G, Deng FM, Aboushwareb T, Turner C, Andersson KE, Santago P, Case D, Sun TT, Christ GJ. J Urol. 2008 May;179(5):2046-51.
● Initial clinical results of the bioartificial kidney containing human cells in ICU patients with acute renal failure.Hodges SJ, Atala A. Curr Urol Rep. 2006 Jan;7(1):41-2.
● Co-author with Anthony Atala on the following book chapters: "Tissue Engineering of Organ Systems" in the book Tissue Engineering and "Tissue-engineered Organs" in the book Principles of Tissue Engineering.
For a complete listing of publications, go to the following link on PubMed, a service provided by the National Library of Medicine: <All>
Karim Kader, M.D., Ph.D.
● Cumulative association of five genetic variants with prostate cancer. Zheng SL, Sun J, Wiklund F, Smith S, Stattin P, Li G, Adami HO, Hsu FC, Zhu Y, Bälter K, Kader AK, Turner AR, Liu W, Bleecker ER, Meyers DA, Duggan D, Carpten JD, Chang BL, Isaacs WB, Xu J, Grönberg H. N Engl J Med. 2008 Feb 28;358(9):910-9. Matrix metalloproteinase polymorphisms are associated with bladder cancer invasiveness.
● Kader AK, Liu J, Shao L, Dinney CP, Lin J, Wang Y, Gu J, Grossman HB, Wu X. Clin Cancer Res. 2007 May 1;13(9):2614-20.
● Matrix metalloproteinase polymorphisms and bladder cancer risk. Kader AK, Shao L, Dinney CP, Schabath MB, Wang Y, Liu J, Gu J, Grossman HB, Wu X. Cancer Res. 2006 Dec 15;66(24):11644-8.
For a complete listing of publications, go to the following link on PubMed, a service provided by the National Library of Medicine: <All>
John McConnell, M.D.
● Long-term treatment with finasteride results in a clinically significant reduction in total prostate volume compared to placebo over the full range of baseline prostate sizes in men enrolled in the MTOPS trial. Kaplan SA, Roehrborn CG, McConnell JD, Meehan AG, Surynawanshi S, Lee JY, Rotonda J, Kusek JW, Nyberg LM Jr; Medical Therapy of Prostatic Symptoms Research Group. J Urol. 2008 Sep;180(3):1030-2; discussion 1032-3.
● Prostate cancer disease-free survival after radical retropubic prostatectomy in patients older than 70 years compared to younger cohorts. Malaeb BS, Rashid HH, Lotan Y, Khoddami SM, Shariat SF, Sagalowsky AI, McConnell JD, Roehrborn CG, Koeneman KS. Urol Oncol. 2007 Jul-Aug;25(4):291-7.
● Association of the circulating levels of the urokinase system of plasminogen activation with the presence of prostate cancer and invasion, progression, and metastasis. Shariat SF, Roehrborn CG, McConnell JD, Park S, Alam N, Wheeler TM, Slawin KM. J Clin Oncol. 2007 Feb 1;25(4):349-55.
For a complete listing of publications, go to the following link on PubMed, a service provided by the National Library of Medicine: <All>
Gordon McLorie, M.D.
● Study Rationale and Design Issues of the Randomized Intervention for Children with Vesicoureteral Reflux (RIVUR). Gordon McLorie, M.D. Keren, R, Carpenter, MA, Hoberman, A, Shaikh, N, Matoo, T, Chesney, RW, Matthews, R, Gerson, A, Greenfield, S, Fivush, B, McLorie, GA, Rushton, HG, Canning, D, Nelson, C, Greenbaum, L, Bukowski, T, Primack, W, Sutherland, R, Hosking, J, Stewart, D, Elder, J, Moxey-Mims, M, Nyberg, L. Journal of the American Academy of Pediatrics, 2008: Vol 122(5): pp. 5240-5250
● Vesicoureteral reflux: where have we been, where are we now, and where are we going? McLorie GA. Adv. Urol. 2008, [Epub 2009 Oct 9]
● Comparison of traditional enterocystoplasty and seromuscular colocystoplasty lined with urothelium. Bandi G, Al-Omar O, McLorie GA. J Pediatr Urol. 2007 Dec;3(6):484-9.
● The bear paw: A radiologic sign for congenital ureteropelvic junction obstruction.
Terlecki RP, McLorie GA. J Pediatr Urol. 2007 Dec;3(6):466-8.
● Continent urinary diversion with a urachal remnant. Al-Omar O, Fisher MB, McLorie GA. J Pediatr Urol. 2005 Oct;1(5):361-3.
For a complete listing of publications, go to the following link on PubMed, a service provided by the National Library of Medicine: <All>
Joseph Pettus, M.D.
● Preservation of Ejaculation in Patients Undergoing Nerve-Sparing Postchemotherapy Retroperitoneal Lymph Node Dissection for Metastatic Testicular Cancer. Pettus JA, Carver BS, Masterson T, Stasi J, Sheinfeld J.Urology. 2008 Nov 19.
● Effect of baseline glomerular filtration rate on survival in patients undergoing partial or radical nephrectomy for renal cortical tumors. Pettus JA, Jang TL, Thompson RH, Yossepowitch O, Kagiwada M, Russo P.Mayo Clin Proc. 2008 Oct;83(10):1101-6.
● A role for neoadjuvant gemcitabine plus cisplatin in muscle-invasive urothelial carcinoma of the bladder: a retrospective experience. Dash A, Pettus JA 4th, Herr HW, Bochner BH, Dalbagni G, Donat SM, Russo P, Boyle MG, Milowsky MI, Bajorin DF. Cancer. 2008 Nov 1;113(9):2471-7.
For a complete listing of publications, go to the following link on PubMed, a service provided by the National Library of Medicine: <All>
John J. Smith III, M.D.
● Correlation Between Urodynamic Function and 3D Cat scan Anatomy in Neobladders. Does it Exist? Crivellaro,S Mami, E. Wald , C. Smith JJ. et al. Neuro Urodyn Jan 2009 pg 1 - 5.
● Kocjanci E, Crivellaro S,Smith JJ III,et al Adjustable Continence Therapy (ACT) for Treatment of Recurrent Female Urinary Incontinence J of Endourology JULY 2008,(22),7, pg 1403 - 07.
● Mixed incontinence: does preoperative urodynamic detrusor overactivity affect postoperative quality of life after pubovaginal sling? Stoffel JT, Smith JJ, Crivellaro S, Bresette JF. Int Braz J Urol. 2008 Nov-Dec;34(6):765-71; discussion 771.
For a complete listing of publications, go to the following link on PubMed, a service provided by the National Library of Medicine: <All>