
Professor of Internal Medicine
Education
Publications | John R. Crouse, III, M.D., is Professor of Medicine and Public Health Sciences and is currently Associate Director of the Wake Forest University School of Medicine (WFUSM) General Clinical Research Center. He is a past recipient of the Preventive Cardiology Academic Award from NHLBI and director of the Wake Forest University Preventive Cardiology Program. The Preventive Cardiology Program involves clinical activities (the Clinical Lipid Center, a tertiary referral clinic for difficult to manage dyslipidemia patients), research, and teaching. Research interests include lipids, nutrition, and interrelationships of atherosclerosis of and risk factors for cerebrovascular, peripheral vascular, an coronary artery disease.
Dr. Crouse's important academic contributions include establishment of use of B-mode ultrasound for quantification of subclinical atherosclerosis in epidemiologic studies and clinical trials, and identification of statin treatment as a means of reducing risk of stroke. Current NIH-funded research includes (1) a clinical trial to test the hypothesis that treatment with azithromycin reduces the risk of CHD; (2) a study to test the hypothesis that impairment of vascular function identifies older individuals at increased risk of CHD; and, (3) an epidemiologic evaluation of interassociations between indices of arterial structure and function in patients with defined coronary status. The Preventive Cardiology Program also hosts a yearly CME program, the Chetola Conference, devoted to dyslipidemia and vascular disease prevention. |
1. Crouse JR, Grundy SM. Evaluation of a continuous isotope feeding method for measurement of cholesterol absorption in man. J Lipid Res 1978;19:967-971. 2. Crouse JR. Gender, lipoproteins, diet and cardiovascular risk. Lancet 1989;1:318-320. 3. Crouse JR, Harpold GH, Kahl FR, Toole JF, McKinney WM. Evaluation of a scoring system for extracranial carotid atherosclerosis extent with B-mode ultrasound. Stroke 1986;17:270-275. 4 Crouse JR, Toole JF, McKinney WM, Dignan MB, Howard G, Kahl FR, McMahan MR, Harpold GH. Risk factors for extracranial carotid artery atherosclerosis. Stroke 1987;18:990-996. 5 Craven TE, Ryu JE, Espeland MA, Kahl FR, McKinney WM, Toole JF, McMahan MR, Thompson C, Heiss G, Crouse JR. Evaluation of the associations between carotid artery atherosclerosis and coronary artery stenosis: A case control study. Circulation 1990;82:1230-1242. 6 Crouse JR, III, Byington RP, Bond MG, Espeland MA, Craven TE, Sprinkle JW, McGovern ME, Furberg C. Pravastatin, lipids, and atherosclerosis in the carotid arteries (PLAC-II). Am J Cardiol 1995;75:455-459. 7 Crouse JR, III, Goldbourt U, Evans G, Pinsky J, Sharrett AR, Sorlie P, Riley W, Heiss G. Risk Factors and Segment Specific Carotid Arterial Enlargement in the Atherosclerosis Risk in Communities (ARIC) Cohort. Stroke 1996;27:69-75. 8. Crouse JR III, Byington RP, Hoen HM, Furberg C. Reductase inhibitor monotherapy and stroke prevention. Arch Int Med 1997; 157: 1305-1310. |