Upcoming or Currently Enrolling Clinical Trials
In Gastroenterology
ACCORDIS:
IRB approval # BG 05-254
A Double Blinded, Randomized Parallel Arm, Dose Ranging Study of IMURAN in Subjects with Active Crohn’s Disease Requiring Treatment with Prednisone: A Crohn’s Disease Optimal Range Dose of Imuran Study.
We are currently recruiting subjects who have been diagnosed with Crohn’s Disease for at least 3 months and require treatment with oral prednisone or budesonide (ENTOCORT). The length of participation in the study is approximately 9 months.
For more information please contact: Angie Boaz LPN CCRC (336) 713-7319
Open Label, Pilot Study of the Use of Conjugated Linoleic Acid in Subjects with Crohn’s Disease.
IRB approval # BG
This study is currently not open for enrollment
We will be looking for subjects between the ages of 18-50 years of age that have been diagnosed with Crohn’s disease by clinical criteria. Patients will be enrolled in the study for approximately 14 weeks. Subjects will consume the CLA supplement once daily for 12 weeks.
Compensation for time and travel may be available.
For more information please contact Angie Boaz LPN CCRC (336) 713-7319
A Pilot Study of the Effects of Dietary Soy Supplementation of Crohn’s Disease
IRB approval # BG 05-399
Currently we are looking for subjects 18 years of age and older with a diagnosis of Crohn’s disease. You must be willing to consume a soy supplement twice a day for 12 weeks. You can not have intolerance to soy or milk products. Subjects will also complete a daily diary and questionnaires at each clinic visit.
For more information please contact Angie Boaz LPN CCRC (336) 713-7319
Evaluation of Tropical 10% Metronidazole Ointment for the Treatment of Active Perianal Crohn’s Disease
IRB approval # BG 05-567
Currently we are looking for patients that have been diagnosed with Crohn’s disease with anorectal involvement. You must have had perianal symptoms for at least 3 months. Subjects will participate in the study for approximately 8 weeks.
For more information please contact Angie Boaz LPN CCRC (336) 713-7319
Assessment of Whole Gut Transit Time UsingThe SmartPill Capsule
Human Protocol: IRB#00000393
Currently enrolling subjects between ages of 18-80 years of age and who are healthy or have severe constipation (constipation symptoms for at least 1 year duration). You will participate in this study for about two to four weeks. You will receive compensation for your participation.
For more information please call Judy Hooker at 336-713-7301
The Effect of Enzyme Supplements on Meal-Related Upper Gastrointestinal Symptoms and Gastric Myoelectrical Activity in Healthy Subjects and Patients with Functional Dyspepsia
BG# 04-353
Currently enrolling people age 18 and older diagnosed with functional dyspepsia: a condition that refers to upper abdominal discomfort, fullness, early satiety, and nausea and vomiting that occur after ingestion of meals. This study is being done to determine the effect of enzyme supplementation on meal related upper GI symptoms. You will participate in this study approximately 3 weeks. You will receive compensation for your participation.
For more information please call Judy Hooker at 336-713-7301
The Effect of Calcium Dietary Supplements on Upper Gastrointestinal Symptoms and Gastric Myoelectrical Activity in Healthy Women
Human Protocol: IRB00000608
Currently enrolling, healthy, women ages 50 to 70. This is a study to determine the incidence of nausea, bloating, and other upper GI symptoms in healthy subjects before and after ingestion of calcium supplements. Your will be required to make 5 visits to our clinic. You will receive compensation for your participation.
For more information please call Judy Hooker at 336-713-7301
(NIH) Gastroparesis Registry
Human Protocol:
This will be enrolling pending IRB approval
We will be enrolling subjects with gastroparesis. To be eligible for this study, you must be at least 18 years old and must have delayed gastric emptying and/or nausea combined with other symptoms of gastroparesis (vomiting, early satiety, and abdominal pain). Your participation could last up to four years or longer.
For more information please call Judy Hooker at 336-713-7301
The Digestive Health Center's Main Telephone
Number is (336) 713-7777.