There is no single test used to establish a diagnosis of ALS. However, specially selected tests are performed to rule out other diseases. Those studies include: Neurological Examination: the physician will test muscle strength, reflexes, sensation, walking, speech, swallowing, and other functions. The following abnormalities are frequently found by the examining physician in patients with ALS: brisk reflexes, stiff arms and legs, uninhibited laughing or crying, wasting of muscles, weakness, muscle twitching and cramps. Electromyography (EMG): the physician places a needle into a muscle and evaluates its function. Nerve Conduction Studies: examine the integrity of nerves by electrical stimulation. |  Electromyography may be used in diagnosing ALS.
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