| William D. Wagner, Ph.D. Professor, Surgical Sciences — Plastic/Reconstructive | | Undergraduate: | B.S., Geneva College, 1964 | | Graduate: | M.S., West Virginia University, 1967
Ph.D., West Virginia University, 1970 | | Teaching: | Basic biochemistry and physiology, Pathobiology, Wound repair, Inflammation, Structure and function of connective tissue, Proteoglycan structure and function | | Academic Positions: | 1972 – 1973 Instructor, Department of Comparative Medicine, Bowman Gray School of Medicine of Wake Forest University, Winston-Salem, NC
1973 – 1978 Assistant Professor, Department of Comparative Medicine, Bowman Gray School of Medicine of Wake Forest University, Winston-Salem, NC
1978 -1983 Associate Professor, Department of Comparative Medicine, Bowman Gray School of Medicine of Wake Forest University, Winston-Salem, NC
1983 – 1997 Professor, Department of Comparative Medicine, Bowman Gray School of Medicine of Wake Forest University, Winston-Salem, NC
1997 - 2006 Professor, Department of Pathology, Bowman Gray School of Medicine, Winston-Salem, NC
2006 - present Professor, Department of Plastic & Reconstructive Surgery, Wake Forest University Health Sciences, Winston-Salem, NC | | Special Areas of Interest: | Biomedical engineering; Wound repair; Nanomedicine;Cardiovascular diseases; Connective tissue diseases; Smooth muscle cell, keratinocytes and macrophage cell biology; Extracellular matrix. | | Affiliate Faculty | Virginia Tech – Wake Forest UniversitySchool of Biomedical Engineering and Sciences
Center for Nanotechnology and Molecular Materials Wake Forest University
Associate, Regenerative Medicine Institute Wake Forest University School of Medicine
Associate, Translational Science Institute Wake Forest University School of Medicine | | Memberships Include: | American Heart Association
Council on nutrition, physical activity and metabolism
Council on arteriosclerosis, thrombosis, and vascular biology
Fellow, American Heart Association
American Society for Investigative Pathology
American Association of Pathologists, Inc.
American Association for the Advancement of Science
North American Vascular Biology Organization
Biomedical Engineering Society | | PATENTS/INTELLECTUALPROPERTY Pub. App. No | Title | | 61/081,997
Filed: 7/18/08 | Resorbable and degradable apparati for negative pressure treatment of internal or deep tissue injuries
Inventors: Louis C. Argenta, M.D.
Michael J. Morykwas, Ph.D.
William D. Wagner, Ph.D.
Nicole Levi-Polyachenko, Ph.D.
Jie Liu. Ph.D., Ph.D. | WFU App. 08-50 | Palatal transport system
Inventors: William D. Wagner, Ph.D.
Nicole Levi-Polyachenko, Ph.D.
Louis C. Argenta, M.D.
Claire Sanger, D.O.
Tabitha Rosenbalm, M.S | 60/979,963
Filed: 10/14/08 | Methods and compositions for printing biologically compatible nanotubes composites for autologous tissue
Inventors: David Carroll, Ph. D.
William D. Wagner, Ph. D.
Nicole Levi-Polyachenko, Ph. D.
Louis C. Argenta, M.D.
Michael J. Morykwas, Ph.D. | 6,221,855
Filed: 4/24/01 | Regulation of nucleic acid expression by heparan sulfate and biological equivalents thereof.
Inventor: William D. Wagner, Ph.D | WFU App. 08-38
Filed: 4/11/08 | Nanocomposite hyperthermic wound healing dressing
Inventors: Louis C. Argenta, M.D
Michael J. Morykwas, Ph.D.
William D. Wagner, Ph. D.
Nicole Levi-Polyachenko, Ph.D.
Faith M. Coldren, Ph.D.
Joseph A. Molnar, M.D., Ph.D | 61/088,558 Filed: 8/13/08 | Apparatus and method for cardiac tissue modulation by topical application of vacuum to minimize cell death and damage
Inventors: Louis C. Argenta, M.D
David Carroll, Ph.D.
Michael J. Morykwas, Ph.D.
James E. Jordan, Ph.D
William D. Wagner, Ph.D. | WO2008/108820
Filed: 9/12/07
Published: 9/12/08 | Small-scale pressure sensors
Inventors: David Carroll, Ph.D
Faith M. Coldren, Ph.D.
Nicole Levi-Polyachenko, Ph.D.
Lawrence X. Webb, M.D.
William D. Wagner, Ph. D.
Thomas L. Smith, Ph.D
Briam Wemer, M.S | Recent Publications: | | | Coldren FM, Palavecino EL, Levi-Polyachenko NH, Wagner WD, Smith TL, Smith BP, Webb LX, Carroll DL. Encapsulated staphylococcus aureus strains vary in adhesiveness assessed by atomic force microscopy. J Biomed Mater Res A. 2008 Apr 22. Wagner WD, Guo F, Jokinen MP. Artery regional properties and atherosclerosis susceptibility..Life Sci. 2007 Jan 2;80(4):299-306. Guo F, Zarella C, Wagner WD. STAT4 and the proliferation of artery smooth muscle cells in atherosclerosis. Exp Mol Pathol. 2006 Aug;81(1):15-22. McGee MP, Wagner WD. Dermatan sulfate anticoagulant efficiency is regulated by osmotic stress.Matrix Biology 2004; 23:363-370 McGee M, Wagner WD. Chondroitin sulfate anticoagulant activity is linked to water transfer. Relevance to versican structure in atherosclerosis. ATVB 2003;23:1921-27. Shirk RA, Parthasarathy N, San Antonio JD, Church FC, Wagner WD. Altered dermatan sulfate structure and reduced heparin cofactor II-stimulating activity of biglycan and decorin from human atherosclerotic plaque.J Biol Chem. 2000 Jun 16;275(24):18085-92 Geary RL, Nikkari ST, Wagner WD, Williams JK, Adams MR, Dean RH. Wound healing: a paradigm for lumen narrowing after arterial reconstruction..J Vasc Surg. 1998 Jan;27(1):96-106; discussion 106-8. Parthasarathy N, Goldberg IJ, Sivaram P, Mulloy B, Flory DM, Wagner WD. Oligosaccharide sequences of endothelial cell surface heparan sulfate proteoglycan with affinity for lipoprotein lipase. J Biol Chem. 1994 Sep 2;269(35):22391-6. | | Current Abstracts: | | | Levi-Polyachenko N, Merkel B, Jones W, Wagner W, Carroll J, Stewart J. Multi-wallled carbon nanotubes increase the efficiency of hyperthermic chemotherapy. Abstract. Presented at the 12th Annual NSTI Nanotechnology Conference, Houston, TX. May 3-7, 2008. Argenta L, Morykwas M, Zheng Z, Wagner W, Tatter S. Controlled negative pressure reduces brain edema and modulates brain metabolites in a brain injury model. J Neurotrauma, 25(7), p930, 2008. Levi-Polyachenko N, Rosenbalm T, Namboothry M, Zheng Z, Carroll D, Argenta L, Morykwas M, Wagner W. Abstract. Biomedical Engineering Society, St. Louis, MO. October 2-4, 2008. Rosenbalm T, Levi-Polyachenko N, Argenta L, Wagner, W. Novel bioresorbable elastomeric nanocomposites useful for cleft palate reconstruction. Abstract. Presented at Resident Research Day, Wake Forest University School of Medicine, Winston-Salem, NC. November 20, 2008. Liu J. Production of a nanocomposite for tissue repair application requiring viscoelasticity Federation of American Societies for Experimental Biology, 2009 Wagner W, Liu J, Morykwas M, Argenta L. Biodegradable polymers useful in wound repair requiring negative pressure wound therapy Federation of American Societies for Experimental Biology, 2009 Rosenbalm T, Levi-Polyachenko N, Argenta L, Wagner, W. Novel bioresorbable elastomeric nanocomposites useful for cleft palate reconstruction Federation of American Societies for Experimental Biology, 2009 | |
Click Here for highlights of Dr. Wagner’s Published Literature PubMed |